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COX2/Cyclooxygenase 2 Rabbit pAb
AO-06-EA024-50
Antibody Product Overview
| ELK.No | EA024 |
| Product name | COX2/Cyclooxygenase 2 Rabbit pAb |
| Reactivity | Human |
| Applications | WB, IHC |
| Other name | Cyclooxygenase 2, GRIPGHS, hCox 2, PGG/HS, PGH synthase 2, PGHS 2, PHS 2, PHS II, Prostaglandin G/H synthase 2, Prostaglandin H2 synthase 2, PTGS2 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5743 |
| Human Swiss-Prot | P35354 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
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| Immunogen | Synthetic Peptide |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:1,000 IHC 1:100 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 70kDa |
| Background | Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme that in humans is encoded by the PTGS2 gene. There are two isozymes of COX encoded by distinct gene products: a constitutive COX-1 (this enzyme) and an inducible COX-2, which differ in their regulation of expression and tissue distribution. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. A splice variant of COX-1 termed COX-3 was identified in the CNS of dogs, but does not result in a functional protein in humans. Two smaller COX-1-derived proteins (the partial COX-1 proteins PCOX-1A and PCOX-1B) have also been discovered, but their precise roles are yet to be described. |
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Additional Images
Western blot analysis of Hela with COX2 Rabbit Polyclonal antibody diluted at 1:1,000.
: AO-06-EA024-50
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