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Antibody Product Overview
| ELK.No | EA147 |
| Product name | β-Catenin Rabbit pAb |
| Reactivity | Mouse, Rat |
| Applications | WB, IHC |
| Other name | beta catenin, b-catenin, CTNB1, CTNNB1, FLJ25606, OTTHUMP00000162082 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 1499 |
| Human Swiss-Prot | P35222 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:1,000 IHC 1:500-1,000 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 92kDa |
| Background | The distinct peripheral cytosolic proteins, alpha, beta and gamma catenin (102, 94 and 86 kDa) are found in many tissues and bind to the conserved cytoplasmic tail domain of the cell adhesion cadherins. Catenins link E cadherin to other integral membrane or cytoplasmic proteins and are modulated by Wnt1 proto oncogene. The central core region of beta catenin is involved in mediation of cadherin catenin complex interaction with EGFR. Beta-Catenin-mediated signalling is involved at several stages of vertebrate neural development. |
| Function | |
| Subcellular location | Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Membrane, Nucleus, Synapse |
| Expression |
Additional Images
Western blot analysis of 1) 3T3, 2)Rat Liver, with β-Catenin Rabbit pAb EA147 diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded human breast caricnoma using β-catenin（EA147）Rabbit pAb diluted at 1:500.
: AO-06-EA147-50
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