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Antibody Product Overview
| ELK.No | EA213 |
| Product name | IκB α Rabbit pAb |
| Reactivity | Human, Rat |
| Applications | WB, IHC |
| Other name | I kappa B alpha antibody, IkB-alpha antibody, IKBA antibody, MAD3 antibody, NFKB inhibitor antibody |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 4792 |
| Human Swiss-Prot | P25963 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
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| Human Swiss link | |
| Mouse gene ID | |
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| Rat gene ID | |
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| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:2,000-5,000 IHC 1:200-500 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 40kDa |
| Background | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. IκBα phosphorylation and resulting Rel-dependent transcription are activated by a highly diverse group of extracellular signals including inflammatory cytokines, growth factors, and chemokines. |
| Function | |
| Subcellular location | Cytoplasm,Nucleus |
| Expression |
Additional Images
Western blot analysis of 1) Hela, 2)PC12 with IκB α Rabbit pAb EA213 diluted at 1:2,000.
Immunohistochemical analysis of paraffin-embedded Human KidneyTissue using I κB α （EA213）Rabbit pAb diluted at 1:500.
: AO-06-EA213-100
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