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Antibody Product Overview
| ELK.No | EA320 |
| Product name | VEGF Rabbit pAb |
| Reactivity | Human, Rat, Mouse |
| Applications | IHC |
| Other name | VEGFA antibody, VPF antibody, VEGF120 antibody, Vascular endothelial growth factor antibody |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 7422 |
| Human Swiss-Prot | P15692 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | IHC 1:200-500 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 23,45kDa |
| Background | VEGFA, also named as VEGF or VPF, belongs to the PDGF/VEGF growth factor family. It is a growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. VEGFA induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. Defects in VEGFA are associated with microvascular complications of diabetes type 1 (MVCD1). VEGFA has 17 isoforms with MW from 16 to 45 kDa. Some isoforms have homodimer forms (e.g.; VEGFA189 38kDa or VEFGA110 34kDa). VEGF-A exists in at least seven homodimeric isoforms. The monomers consist of 121, 145, 148, 165, 183, 189, or 206 amino acids (PMID:15602010 ). This antibody can recognize all VEGFA isoforms. |
| Function | |
| Subcellular location | Secreted |
| Expression |
Additional Images
Immunohistochemical analysis of paraffin-embedded Human Liver Carcinoma Tissue using VEGF（EA320）Rabbit pAb diluted at 1:500.
Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using VEGF（ EA320 ）Rabbit pAb diluted at 1:500.
Immunohistochemical analysis of paraffin-embedded Human Stomach Carcinoma Tissue using VEGF（ EA320 ）Rabbit pAb diluted at 1:500.
: AO-06-EA320-50
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