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Antibody Product Overview
| ELK.No | EA345 |
| Product name | MEK3 Rabbit pAb |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Other name | MAP2K3; MKK3; PRKMK3; Dual specificity mitogen-activated protein kinase kinase 3; MAP kinase kinase 3; MAPKK3; MAPK/ERK kinase 3 |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5606 |
| Human Swiss-Prot | P46734 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | IHC 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 34,39kDa |
| Background | Three alternatively spliced transcript variants of MEK3 encoding distinct isoforms have been reported. Isoform B utilizes a different start codon compared to isoform C resulting in the production of a N-terminal segment of isoform B which is shorter and distinct from isoform C . MEK3b is the predominant form of MEK3 and strongly activates p38 MAP kinase . |
| Function | |
| Subcellular location | Cytosol,Nucleus |
| Expression |
Additional Images
Immunohistochemical analysis of paraffin-embedded Human Breast Carcinoma Tissue using MEK3 （EA345）Rabbit pAb diluted at 1:200.
Immunohistochemical analysis of paraffin-embedded Human Kidney Tissue using MEK3 （EA345）Rabbit pAb diluted at 1:200
: AO-06-EA345-50
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