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Antibody Product Overview
| ELK.No | EA367 |
| Product name | Kininogen 1 Rabbit pAb |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Other name | BDK, Fitzgerald factor, HMWK, Ile Ser Bradykinin Bradykinin, Kallidin I Lysyl bradykinin, kininogen 1, KNG, KNG1 |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 3827 |
| Human Swiss-Prot | P01042 |
| Source | Rabbit |
| Isotype | IgG |
| Target | |
| Fields | |
| Gene name | |
| Protein name | |
| Human gene link | |
| Human Swiss link | |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Recombinant Protein |
| Specificity | |
| Formulation | |
| Clonality | Polyclonal |
| Dilution | WB 1:1500-1,000 IHC 1:100-200 |
| Purification | |
| Concentration | 1mg/mL |
| Storage stability | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Molecular Weight (Da) | |
| Observed band (KD) | 45-120kDa |
| Background | Kininogens are inhibitors of thiol proteases; HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects. LMW-kininogen inhibits the aggregation of thrombocytes; LMW-kininogen is in contrast to HMW-kininogen not involved in blood clottingUCHL1, UCHL3, UCHL5/UCH37, and BRCA-1-associated protein-1 (BAP1) belong to the UCH family of DUBs, which all posses a conserved catalytic domain (UCH domain) of about 230 amino acids. UCHL1 is abundantly expressed in neuronal tissues and testes. |
| Function | |
| Subcellular location | Secreted |
| Expression |
Additional Images
Western blot analysis of 1) Human Serum, 2) Rat Kidney Tissue Lysate , 3) Mouse Kidney Tissue Lysate using （EA367）Rabbit pAb diluted at 1:1000.
: AO-06-EA367-100
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