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Cleaved-Cathepsin Z (L62) rabbit pAb
AO-06-ES1033-50
Antibody Product Overview
| ELK.No | ES1033 |
| Product name | Cleaved-Cathepsin Z (L62) rabbit pAb |
| Reactivity | Human;Monkey |
| Applications | WB;ELISA |
| Other name | CTSZ; Cathepsin Z; Cathepsin P; Cathepsin X |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 1522 |
| Human Swiss-Prot | Q9UBR2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | Cathepsin Z |
| Fields | >>Lysosome;>>Apoptosis |
| Gene name | CTSZ |
| Protein name | Cathepsin Z |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9WUU7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CATZ. AA range:43-92 |
| Specificity | Cleaved-Cathepsin Z (L62) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin Z protein resulting from cleavage adjacent to L62. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 27kD |
| Background | The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008], |
| Function | catalytic activity:Release of C-terminal amino acid residues with broad specificity, but lacks action on C-terminal proline. Shows weak endopeptidase activity.,function:Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.,similarity:Belongs to the peptidase C1 family.,tissue specificity:Widely expressed., |
| Subcellular location | Lysosome. |
| Expression | Widely expressed. |
Additional Images
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Western Blot analysis of various cells using Cleaved-Cathepsin Z (L62) Polyclonal Antibody
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Western blot analysis of lysates from COS7 cells, treated with etoposide 25uM 1h, using CATZ (Cleaved-Leu62) Antibody. The lane on the right is blocked with the synthesized peptide.
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: AO-06-ES1033-50
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