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Antibody Product Overview
| ELK.No | ES10335 |
| Product name | SYT4 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6860 |
| Human Swiss-Prot | Q9H2B2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SYT4 |
| Fields | |
| Gene name | SYT4 KIAA1342 |
| Protein name | Synaptotagmin-4 (Synaptotagmin IV) (SytIV) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P40749 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P50232 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SYT4 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 46kD |
| Background | cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,tissue specificity:Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus., |
| Function | cofactor:Binds 3 calcium ions per subunit. The ions are bound to the C2 domains.,function:May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,tissue specificity:Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus., |
| Subcellular location | Cytoplasmic vesicle, secretory vesicle, neuronal dense core vesicle membrane ; Single-pass membrane protein . |
| Expression | Expressed in melanocytes (PubMed:23999003). Expressed in brain. Within brain, expression is highest in hippocampus, with substantial levels also detected in amygdala and thalamus (PubMed:23999003). |
Additional Images
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Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10335-50
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