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Antibody Product Overview
| ELK.No | ES10537 |
| Product name | FA58A rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 92002 |
| Human Swiss-Prot | Q8N1B3 |
| Source | Rabbit |
| Isotype | IgG |
| Target | FA58A |
| Fields | |
| Gene name | FAM58A |
| Protein name | Cyclin-related protein FAM58A (Cyclin-M) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8QZR8 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q4QQW5 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Specificity | FA58A Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 27kD |
| Background | Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly, telecanthus and anogenital and renal malformations. The protein encoded by this gene contains a cyclin-box-fold domain which suggests it may have a role in controlling nuclear cell division cycles. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008], |
| Function | disease:Defects in FAM58A are the cause of toe syndactyly, telecanthus, and anogenital and renal malformations (STAR) [MIM:300707]; also known as STAR syndrome or syndactyly with renal and anogenital malformations.,function:May have a role in cell proliferation.,similarity:Belongs to the cyclin family. Cyclin-like FAM58 subfamily.,subunit:Interacts with SALL1., |
| Subcellular location | cyclin-dependent protein kinase holoenzyme complex,nucleus, |
| Expression | B-cell,Blood,Kidney,Lung, |
Additional Images
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Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10537-100
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