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Antibody Product Overview
| ELK.No | ES10669 |
| Product name | TNF18 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 8995 |
| Human Swiss-Prot | Q9UNG2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TNF18 |
| Fields | >>Cytokine-cytokine receptor interaction |
| Gene name | TNFSF18 AITRL GITRL TL6 UNQ149/PRO175 |
| Protein name | Tumor necrosis factor ligand superfamily member 18 (Activation-inducible TNF-related ligand) (AITRL) (Glucocorticoid-induced TNF-related ligand) (hGITRL) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q7TS55 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from part region of human protein AA range: 101-150 |
| Specificity | TNF18 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 21kD |
| Background | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq, Jul 2008], |
| Function | function:Cytokine that binds to TNFRSF18/AITR/GITR. Important for interactions between activated T-lymphocytes and endothelial cells and may modulate T-lymphocyte survival in peripheral tissues.,induction:Up-regulated after stimulation by lipopolysaccharides.,similarity:Belongs to the tumor necrosis factor family.,subunit:Homotrimer .,tissue specificity:Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells., |
| Subcellular location | Cell membrane ; Single-pass type II membrane protein . |
| Expression | Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10669-50
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