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Antibody Product Overview
| ELK.No | ES10763 |
| Product name | CANT1 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 124583 |
| Human Swiss-Prot | Q8WVQ1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CANT1 |
| Fields | >>Purine metabolism;>>Pyrimidine metabolism;>>Metabolic pathways;>>Nucleotide metabolism |
| Gene name | CANT1 SHAPY |
| Protein name | Soluble calcium-activated nucleotidase 1 (SCAN-1) (EC 3.6.1.6) (Apyrase homolog) (Putative MAPK-activating protein PM09) (Putative NF-kappa-B-activating protein 107) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8VCF1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q8K4Y7 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CANT1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 44kD |
| Background | calcium activated nucleotidase 1(CANT1) Homo sapiens This protein encoded by this gene belongs to the apyrase family. It functions as a calcium-dependent nucleotidase with a preference for UDP. Mutations in this gene are associated with Desbuquois dysplasia with hand anomalies. Alternatively spliced transcript variants have been noted for this gene.[provided by RefSeq, Mar 2010], |
| Function | catalytic activity:A nucleoside diphosphate + H(2)O = a nucleotide + phosphate.,cofactor:Calcium.,function:Calcium-dependent nucleotidase with a preference for UDP. The order of activity with different substrates is UDP > GDP > UTP > GTP. Has very low activity towards ADP and even lower activity towards ATP. Does not hydrolyze AMP and GMP.,miscellaneous:Not inhibited by azide.,PTM:N-glycosylated.,similarity:Belongs to the apyrase family.,subcellular location:Processed form: Secreted.,subunit:Monomer.,tissue specificity:Widely expressed., |
| Subcellular location | Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein . Cell membrane . Processed form: Secreted. |
| Expression | Widely expressed. |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES10763-100
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