Français
English
Antibody Product Overview
| ELK.No | ES10810 |
| Product name | CSK22 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 1459 |
| Human Swiss-Prot | P19784 |
| Source | Rabbit |
| Isotype | IgG |
| Target | CSK22 |
| Fields | >>Ribosome biogenesis in eukaryotes;>>NF-kappa B signaling pathway;>>Mitophagy - animal;>>Wnt signaling pathway;>>Adherens junction;>>Alzheimer disease;>>Prion disease;>>Pathways of neurodegeneration - multiple diseases;>>Measles;>>PD-L1 expression and PD-1 checkpoint pathway in cancer |
| Gene name | CSNK2A2 CK2A2 |
| Protein name | Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O54833 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | CSK22 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation., |
| Function | catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.,similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Tetramer composed of an alpha chain, an alpha' and two beta chains. Also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation., |
| Subcellular location | Nucleus . Cytoplasm . Interaction with SIRT6 prevents translocation into the nucleus. . |
| Expression | Ovary, |
Additional Images
No image
Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
No image
No image
No image
: AO-06-ES10810-50
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package