HNF-3α/β/γ (Acetyl Lys264/253/211) rabbit pAb

HNF-3α/β/γ (Acetyl Lys264/253/211) rabbit pAb

ELK Biotechnology
AO-06-ES1101-50

HNF-3α/β/γ (Acetyl Lys264/253/211) rabbit pAb 50μL

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Antibody Product Overview

ELK.NoES1101
Product nameHNF-3α/β/γ (Acetyl Lys264/253/211) rabbit pAb
ReactivityHuman;Mouse;Rat
ApplicationsWB;ELISA
Other nameFOXA1; HNF3A; TCF3A; Hepatocyte nuclear factor 3-alpha; HNF-3-alpha; HNF-3A; Forkhead box protein A1; Transcription factor 3A; TCF-3A; FOXA2; HNF3B; TCF3B; Hepatocyte nuclear factor 3-beta; HNF-3-beta; HNF-3B;Forkhead box protein A2; Transcription factor 3B; TCF-3B; FOXA3; HNF3G; TCF3G; Hepatocyte nuclear factor 3-gamma; HNF-3-gamma; HNF-3G; Fork head-related protein FKH H3; Forkhead box protein A3; Transcription factor 3G; TCF-3G
Size50μL
Unit price ($)148
Human gene ID3169
Human Swiss-ProtP55317
SourceRabbit
IsotypeIgG
TargetHNF-3α/β/γ
Fields
Gene nameFOXA1/FOXA2/FOXA3
Protein nameHepatocyte nuclear factor 3-alpha/Hepatocyte nuclear factor 3-beta/Hepatocyte nuclear factor 3-gamma
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID15375
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtP35582
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID25098
Rat gene linkView Rat Gene
Rat Swiss-ProtP23512
Rat Swiss linkView Rat Swiss-Prot
ImmunogenThe antiserum was produced against synthesized Acetyl-peptide derived from human FOXA1 around the Acetylation site of Lys265. AA range:231-280
SpecificityAcetyl-HNF-3α/β/γ (K264/253/211) Polyclonal Antibody detects endogenous levels of HNF-3α/β/γ protein only when acetylated at K264/253/211.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)
Observed band (KD)50kD
BackgroundThis gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. [provided by RefSeq, Jul 2008],
Functionfunction:Transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes.,online information:Hepatocyte nuclear factors entry,similarity:Contains 1 fork-head DNA-binding domain.,
Subcellular locationNucleus .
ExpressionHighly expressed in prostate and ESR1-positive breast tumors. Overexpressed in esophageal and lung adenocarcinomas.

Additional Images

Image 1
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Western Blot analysis of Jurkat cells using Acetyl-HNF-3α/β/γ (K264/253/211) Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Image 2
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Western Blot analysis of JK cells using Acetyl-HNF-3α/β/γ (K264/253/211) Polyclonal Antibody. Secondary antibody(catalog#:RS0002) was diluted at 1:20000
Image 3
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Western blot analysis of lysate from Jurkat cells, using FOXA1 (Acetyl-Lys265) Antibody.
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: AO-06-ES1101-50
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