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Antibody Product Overview
| ELK.No | ES11035 |
| Product name | GNLY rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10578 |
| Human Swiss-Prot | P22749 |
| Source | Rabbit |
| Isotype | IgG |
| Target | GNLY |
| Fields | |
| Gene name | GNLY LAG2 NKG5 TLA519 |
| Protein name | Granulysin (Lymphokine LAG-2) (Protein NKG5) (T-cell activation protein 519) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | GNLY Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 15kD |
| Background | The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008], |
| Function | function:Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.,induction:By T-cell growth factor and interleukin-2.,PTM:A 9 kDa form is produced by proteolytic processing of a 15 kDa protein.,similarity:Contains 1 saposin B-type domain.,subcellular location:Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.,tissue specificity:Expressed in natural killer and T-cells., |
| Subcellular location | Secreted. Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation. |
| Expression | Expressed in natural killer and T-cells. |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11035-50
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