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Antibody Product Overview
| ELK.No | ES11098 |
| Product name | SPIT2 rabbit pAb |
| Reactivity | Human;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10653 |
| Human Swiss-Prot | O43291 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SPIT2 |
| Fields | |
| Gene name | SPINT2 HAI2 KOP |
| Protein name | Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q9WU03 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SPIT2 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 27kD |
| Background | This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009], |
| Function | domain:This inhibitor contains two inhibitory domains.,function:Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.,similarity:Contains 1 BPTI/Kunitz inhibitor domain.,similarity:Contains 2 BPTI/Kunitz inhibitor domains.,tissue specificity:Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea., |
| Subcellular location | Membrane ; Single-pass type I membrane protein . |
| Expression | Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11098-50
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