Français
English
Antibody Product Overview
| ELK.No | ES11180 |
| Product name | LUM rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 4060 |
| Human Swiss-Prot | P51884 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LUM |
| Fields | >>Proteoglycans in cancer |
| Gene name | LUM LDC SLRR2D |
| Protein name | Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P51885 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P51886 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 30-110 |
| Specificity | LUM Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 37kD |
| Background | This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008], |
| Function | developmental stage:Present in the extracellular matrix of human articular cartilage at all ages, although its abundance is far greater in the adult. In the adult cartilage lumican exists predominantly in a glycoprotein form lacking keratan sulfate, whereas the juvenile form of the molecule is a proteoglycan.,PTM:Sulfated on tyrosine residue(s).,similarity:Belongs to the small leucine-rich proteoglycan (SLRP) family. Class II subfamily.,similarity:Contains 12 LRR (leucine-rich) repeats.,subunit:Binds to laminin.,tissue specificity:Cornea and other tissues., |
| Subcellular location | Secreted, extracellular space, extracellular matrix . |
| Expression | Cornea and other tissues. |
Additional Images
No image
Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night
No image
No image
No image
: AO-06-ES11180-50
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package