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Antibody Product Overview
| ELK.No | ES11507 |
| Product name | MCHR1 rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 2847 |
| Human Swiss-Prot | Q99705 |
| Source | Rabbit |
| Isotype | IgG |
| Target | MCHR1 |
| Fields | >>Neuroactive ligand-receptor interaction |
| Gene name | MCHR1 GPR24 SLC1 |
| Protein name | Melanin-concentrating hormone receptor 1 (MCH receptor 1) (MCH-R1) (MCHR-1) (G-protein coupled receptor 24) (MCH-1R) (MCH1R) (MCHR) (SLC-1) (Somatostatin receptor-like protein) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | Q8JZL2 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P97639 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | MCHR1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 46kD |
| Background | melanin concentrating hormone receptor 1(MCHR1) Homo sapiens The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally similar to somatostatin receptors, this protein does not seem to bind somatostatin. [provided by RefSeq, Jul 2008], |
| Function | caution:It is uncertain whether Met-1, Met-6 or Met-70 is the initiator.,function:Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with NCDN.,tissue specificity:Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart., |
| Subcellular location | Cell membrane; Multi-pass membrane protein. |
| Expression | Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11507-100
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