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Antibody Product Overview
| ELK.No | ES11619 |
| Product name | P2RY1 rabbit pAb |
| Reactivity | Human;Rat;Mouse |
| Applications | WB;ELISA |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 5028 |
| Human Swiss-Prot | P47900 |
| Source | Rabbit |
| Isotype | IgG |
| Target | P2RY1 |
| Fields | >>Rap1 signaling pathway;>>Neuroactive ligand-receptor interaction;>>Platelet activation;>>Taste transduction |
| Gene name | P2RY1 |
| Protein name | P2Y purinoceptor 1 (P2Y1) (ATP receptor) (Purinergic receptor) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P49650 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P49651 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 130-210 |
| Specificity | P2RY1 Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 41kD |
| Background | purinergic receptor P2Y1(P2RY1) Homo sapiens The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008], |
| Function | function:Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation.,induction:Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets.,similarity:Belongs to the G-protein coupled receptor 1 family., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Blood,Brain,Lung,Placenta,Platelet, |
Additional Images
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Western blot analysis of lysates from PC12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11619-100
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