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Antibody Product Overview
| ELK.No | ES11854 |
| Product name | PCY1A rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5130 |
| Human Swiss-Prot | P49585 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PCY1A |
| Fields | >>Phosphonate and phosphinate metabolism;>>Glycerophospholipid metabolism;>>Metabolic pathways;>>Choline metabolism in cancer |
| Gene name | PCYT1A CTPCT PCYT1 |
| Protein name | Choline-phosphate cytidylyltransferase A (EC 2.7.7.15) (CCT-alpha) (CTP:phosphocholine cytidylyltransferase A) (CCT A) (CT A) (Phosphorylcholine transferase A) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | P49586 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P19836 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | PCY1A Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 40kD |
| Background | This gene belongs to the cytidylyltransferase family and is involved in the regulation of phosphatidylcholine biosynthesis. Mutations in this gene are associated with spondylometaphyseal dysplasia with cone-rod dystrophy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2015], |
| Function | catalytic activity:CTP + choline phosphate = diphosphate + CDP-choline.,enzyme regulation:By phosphorylation.,function:Controls phosphatidylcholine synthesis.,pathway:Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 1/2.,PTM:The serine residues of the C-terminus are phosphorylated. The inactive soluble form is stabilized by phosphorylation, the active membrane bound form is promoted by anionic lipids or diacylglycerol, and is stabilized by dephosphorylation.,similarity:Belongs to the cytidylyltransferase family.,subcellular location:It can interconvert between an inactive cytosolic form and an active membrane-bound form.,subunit:Homodimer; disulfide-linked., |
| Subcellular location | Cytoplasm, cytosol . Membrane ; Peripheral membrane protein . Endoplasmic reticulum . Nucleus . It can interconvert between an inactive cytosolic form and an active membrane-bound form. . |
| Expression | Brain, placenta, liver, fetal and adult lung. |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11854-50
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