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Antibody Product Overview
| ELK.No | ES11875 |
| Product name | LSHB rabbit pAb |
| Reactivity | Human;Mouse;Rat |
| Applications | WB;ELISA |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 3972 |
| Human Swiss-Prot | P01229 |
| Source | Rabbit |
| Isotype | IgG |
| Target | LSHB |
| Fields | >>cAMP signaling pathway;>>Neuroactive ligand-receptor interaction;>>GnRH signaling pathway;>>Ovarian steroidogenesis;>>Prolactin signaling pathway;>>GnRH secretion |
| Gene name | LHB |
| Protein name | Lutropin subunit beta (Lutropin beta chain) (Luteinizing hormone subunit beta) (LH-B) (LSH-B) (LSH-beta) |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | O09108 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P01230 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | LSHB Polyclonal Antibody detects endogenous levels of protein. |
| Formulation | Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 ELISA 1:5000-20000 |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 15kD |
| Background | This gene is a member of the glycoprotein hormone beta chain family and encodes the beta subunit of luteinizing hormone (LH). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism. [provided by RefSeq, Jul 2008], |
| Function | disease:Defects in LHB are a cause of hypogonadism [MIM:152780]. Hypogonadism is characterized by infertility and pseudohermaphroditism.,function:Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.,online information:Luteinizing hormone entry,online information:The Singapore human mutation and polymorphism database,similarity:Belongs to the glycoprotein hormones subunit beta family.,subunit:Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin.,tissue specificity:Pituitary gland., |
| Subcellular location | Secreted. |
| Expression | Pituitary gland. |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES11875-50
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