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Antibody Product Overview
| ELK.No | ES12076 |
| Product name | ZRAN1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 54764 |
| Human Swiss-Prot | Q9UGI0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ZRAN1 |
| Fields | |
| Gene name | ZRANB1 TRABID |
| Protein name | ZRAN1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 360216 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q7M760 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ZRAN1 AA range: 255-305 |
| Specificity | This antibody detects endogenous levels of ZRAN1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 78kD |
| Observed band (KD) | |
| Background | |
| Function | domain:The OTU domain mediates the deubiquitinating activity.,domain:The RanBP2-type zinc fingers mediate the specific interaction with 'Lys-63'-linked ubiquitin.,function:Positive regulator of the Wnt signaling pathway that specifically cleaves 'Lys-63'-linked ubiquitin chains. Acts by deubiquitinating APC protein, a negative regulator of Wnt-mediated transcription. May also modulate TNF-alpha signaling.,similarity:Belongs to the peptidase C64 family.,similarity:Contains 1 OTU domain.,similarity:Contains 3 RanBP2-type zinc fingers.,subunit:Interacts with APC and TRAF6.,tissue specificity:Widely expressed., |
| Subcellular location | Cytoplasm . Nucleus . Enriched in punctate localization in the cytoplasm. . |
| Expression | Widely expressed. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12076-100
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