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Antibody Product Overview
| ELK.No | ES12197 |
| Product name | ZMYM3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9203 |
| Human Swiss-Prot | Q14202 |
| Source | Rabbit |
| Isotype | IgG |
| Target | ZMYM3 |
| Fields | |
| Gene name | ZMYM3 DXS6673E KIAA0385 ZNF261 |
| Protein name | ZMYM3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56364 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JLM4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human ZMYM3 AA range: 258-308 |
| Specificity | This antibody detects endogenous levels of ZMYM3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 151kD |
| Observed band (KD) | |
| Background | This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010], |
| Function | disease:A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).,similarity:Contains 9 MYM-type zinc fingers.,subunit:May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I.,tissue specificity:Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta., |
| Subcellular location | Nucleus . |
| Expression | Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta. |
Additional Images
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Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12197-100
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