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Antibody Product Overview
| ELK.No | ES12381 |
| Product name | VCX3 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 51481 |
| Human Swiss-Prot | Q9NNX9 |
| Source | Rabbit |
| Isotype | IgG |
| Target | VCX3 |
| Fields | |
| Gene name | VCX3A VCX3 VCX8R VCXA |
| Protein name | VCX3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human VCX3 AA range: 40-90 |
| Specificity | This antibody detects endogenous levels of VCX3 at Human |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 20kD |
| Observed band (KD) | |
| Background | This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008], |
| Function | disease:Defects in VCX3A are associated with some forms of X-linked nonspecific mental retardation.,function:May mediate a process in spermatogenesis or may play a role in sex ratio distortion.,similarity:Belongs to the VCX/VCY family.,tissue specificity:Expressed exclusively in testis., |
| Subcellular location | nucleus,nucleolus, |
| Expression | Expressed exclusively in testis. |
Additional Images
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Western blot analysis of lysates from A549 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12381-50
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