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Antibody Product Overview
| ELK.No | ES12407 |
| Product name | UT2 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 8170 |
| Human Swiss-Prot | Q15849 |
| Source | Rabbit |
| Isotype | IgG |
| Target | UT2 |
| Fields | |
| Gene name | SLC14A2 HUT2 UT2 |
| Protein name | UT2 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 27411 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R4T9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 54302 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q62668 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human UT2 AA range: 429-479 |
| Specificity | This antibody detects endogenous levels of UT2 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 101kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011], |
| Function | function:Specialized low-affinity vasopressin-regulated urea transporter. Mediates rapid transepithelial urea transport across the inner medullary collecting duct and plays a major role in the urinary concentrating mechanism.,induction:Isoform 1 is induced by low protein in the diet, isoform 2 by dehydration.,similarity:Belongs to the urea transporter family.,subunit:Isoform 1 interacts with SNAPIN which may be important for recruitment to the plasma membrane.,tissue specificity:Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney., |
| Subcellular location | Apical cell membrane; Multi-pass membrane protein. |
| Expression | Isoform 1 and isoform 2 are expressed in the inner medulla of the kidney. |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12407-50
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