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Antibody Product Overview
| ELK.No | ES12441 |
| Product name | UBR3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 130507 |
| Human Swiss-Prot | Q6ZT12 |
| Source | Rabbit |
| Isotype | IgG |
| Target | UBR3 |
| Fields | |
| Gene name | UBR3 KIAA2024 ZNF650 |
| Protein name | UBR3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 68795 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q5U430 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human UBR3 AA range: 1591-1641 |
| Specificity | This antibody detects endogenous levels of UBR3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 208kD |
| Observed band (KD) | |
| Background | |
| Function | function:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Does not bind to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.,pathway:Protein modification; protein ubiquitination.,sequence caution:Translated as Gln.,similarity:Belongs to the UBR1 family.,similarity:Contains 1 RING-type zinc finger.,similarity:Contains 1 UBR-type zinc finger.,subunit:Interacts with UBE2A and UBE2B., |
| Subcellular location | Membrane ; Multi-pass membrane protein . |
| Expression |
Additional Images
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Western blot analysis of lysates from THP-1 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12441-100
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