Français
English
Antibody Product Overview
| ELK.No | ES12457 |
| Product name | UBC rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | |
| Human Swiss-Prot | P0CG48 |
| Source | Rabbit |
| Isotype | IgG |
| Target | UBC |
| Fields | >>PPAR signaling pathway;>>Ubiquitin mediated proteolysis;>>Mitophagy - animal;>>Parkinson disease;>>Pathways of neurodegeneration - multiple diseases;>>Shigellosis;>>Kaposi sarcoma-associated herpesvirus infection |
| Gene name | UBC |
| Protein name | UBC |
| Human gene link | |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 22190 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P0CG50 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 50522 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q63429 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human UBC AA range: 160-210 |
| Specificity | This antibody detects endogenous levels of UBC at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 75kD |
| Observed band (KD) | |
| Background | This gene represents a ubiquitin gene, ubiquitin C. The encoded protein is a polyubiquitin precursor. Conjugation of ubiquitin monomers or polymers can lead to various effects within a cell, depending on the residues to which ubiquitin is conjugated. Ubiquitination has been associated with protein degradation, DNA repair, cell cycle regulation, kinase modification, endocytosis, and regulation of other cell signaling pathways. [provided by RefSeq, Aug 2010], |
| Function | function:Protein modifier which can be covalently attached to target lysines either as a monomer or as a lysine-linked polymer. Attachment to proteins as a Lys-48-linked polymer usually leads to their degradation by proteasome. Attachment to proteins as a monomer or as an alternatively linked polymer does not lead to proteasomal degradation and may be required for numerous functions, including maintenance of chromatin structure, regulation of gene expression, stress response, ribosome biogenesis and DNA repair.,miscellaneous:This ribosomal protein is synthesized as a C-terminal extension protein (CEP) of ubiquitin.,miscellaneous:Ubiquitin is synthesized as a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains. In some species there is a final amino-acid after the last repeat, here in human a Val. Some ubiquitin genes contain a |
| Subcellular location | [Ubiquitin]: Cytoplasm . Nucleus . Mitochondrion outer membrane ; Peripheral membrane protein . |
| Expression |
Additional Images
No image
Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
No image
No image
No image
: AO-06-ES12457-100
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package