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Antibody Product Overview
| ELK.No | ES12517 |
| Product name | TTLL3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Tubulin monoglycylase TTLL3 (EC 6.3.2.-) (HOTTL) (Tubulin--tyrosine ligase-like protein 3) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 26140 |
| Human Swiss-Prot | Q9Y4R7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TTLL3 |
| Fields | |
| Gene name | TTLL3 PRO0207 |
| Protein name | TTLL3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 101100 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | A4Q9E5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human TTLL3 AA range: 357-407 |
| Specificity | This antibody detects endogenous levels of TTLL3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.344% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | |
| Function | function:Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.,similarity:Belongs to the ARPC4 family.,similarity:Contains 1 TTL domain.,subunit:Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC, ARPC4/p20-ARC and ARPC5/p16-ARC., |
| Subcellular location | Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, flagellum axoneme . |
| Expression | Expressed in brain, heart, kidney, testis, liver, lung, muscle, spleen, trachea and colon. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12517-50
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