Français
English
Antibody Product Overview
| ELK.No | ES12549 |
| Product name | TRPC5 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Short transient receptor potential channel 5 (TrpC5) (Transient receptor protein 5) (TRP-5) (hTRP-5) (hTRP5) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 7224 |
| Human Swiss-Prot | Q9UL62 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TRPC5 |
| Fields | >>Axon guidance;>>GnRH secretion |
| Gene name | TRPC5 TRP5 |
| Protein name | TRPC5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 22067 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9QX29 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human TRPC5 AA range: 828-878 |
| Specificity | This antibody detects endogenous levels of TRPC5 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.293% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). [provided by RefSeq, May 2010], |
| Function | function:Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Has also been shown to be calcium-selective (By similarity). May also be activated by intracellular calcium store depletion.,similarity:Belongs to the transient receptor family. STrpC subfamily.,similarity:Contains 2 ANK repeats.,subunit:Interacts with NHERF (By similarity). Interacts with MX1 and RNF24.,tissue specificity:Expressed in brain with higher levels in fetal brain., |
| Subcellular location | Cell membrane ; Multi-pass membrane protein . |
| Expression | Expressed in brain with higher levels in fetal brain. Found in cerebellum and occipital pole. |
Additional Images
No image
Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
No image
No image
No image
: AO-06-ES12549-100
: 10 Items
Hurry! only 10 items left in stock.
Use collapsible tabs for more detailed information that will help customers make a purchasing decision.
Ex: Shipping and return policies, size guides, and other common questions.
- Paste the label on a flat surface on the package
- Make sure that both 1D and 2D barcodes are clearly visible
- Ensure that the label is smooth and isn’t creased or wrinkled
- Check for any tears, dents, holes or scratches
- Pack your product tightly, with the right size packaging
- Ensure both barcodes are on a flat surface of the package