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Antibody Product Overview
| ELK.No | ES12594 |
| Product name | TRAIP rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10293 |
| Human Swiss-Prot | Q9BWF2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TRAIP |
| Fields | |
| Gene name | TRAIP RNF206 TRIP |
| Protein name | TRAIP |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 22036 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8VIG6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human TRAIP AA range: 399-449 |
| Specificity | This antibody detects endogenous levels of TRAIP at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 52kD |
| Observed band (KD) | |
| Background | This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis. [provided by RefSeq, Jul 2008], |
| Function | function:Inhibits activation of NF-kappa-B mediated by TNF.,similarity:Contains 1 RING-type zinc finger.,subunit:Binds TRAF1 and TRAF2 and is part of the receptor-TRAF signaling complex (By similarity). Interacts with CYLD., |
| Subcellular location | Nucleus, nucleoplasm . Nucleus, nucleolus . Chromosome . Cytoplasm. Cytoplasm, perinuclear region . In the nucleus, found in close proximity to PCNA, suggesting localization at replication foci (PubMed:26595769). Localizes to DNA damage sites in response to replication stress (PubMed:26781088, PubMed:26595769, PubMed:26711499). . |
| Expression |
Additional Images
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Western blot analysis of lysates from VEC cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12594-100
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