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Antibody Product Overview
| ELK.No | ES12596 |
| Product name | TRAD1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 10906 |
| Human Swiss-Prot | O14545 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TRAD1 |
| Fields | |
| Gene name | TRAFD1 FLN29 |
| Protein name | TRAD1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 231712 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q3UDK1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | Q99MM4 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human TRAD1 AA range: 52-102 |
| Specificity | This antibody detects endogenous levels of TRAD1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 64kD |
| Observed band (KD) | |
| Background | The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses (Sanada et al., 2008 [PubMed 18849341]).[supplied by OMIM, Dec 2009], |
| Function | function:May function as a lipopolysaccharide (LPS)-inducible negative regulator in innate immunity. May be involved in endotoxin tolerance. Seems to act as a negative regulator in toll-like receptor signaling.,induction:LPS, IFNB1 and IFNG increased protein levels in RAW cells with IFNB1 being most potent inducer. IL4 and IL10 did not induced the expression in RAW cells, moreover, LPS did not induce expression in the presence of IL4 or IL10.,similarity:Contains 1 TRAF-type zinc finger.,subunit:Interacts with TRAF6., |
| Subcellular location | |
| Expression |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12596-100
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