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Antibody Product Overview
| ELK.No | ES12650 |
| Product name | TM55A rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 55529 |
| Human Swiss-Prot | Q8N4L2 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TM55A |
| Fields | >>Phosphatidylinositol signaling system |
| Gene name | TMEM55A |
| Protein name | TM55A |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 72519 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9CZX7 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 362490 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4V888 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human TM55A AA range: 33-83 |
| Specificity | This antibody detects endogenous levels of TM55A at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 28kD |
| Observed band (KD) | |
| Background | TMEM55A catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al., 2005 [PubMed 16365287]).[supplied by OMIM, Mar 2008], |
| Function | catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,catalytic activity:1-phosphatidyl-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate.,function:Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.,tissue specificity:Ubiquitous., |
| Subcellular location | Late endosome membrane ; Multi-pass membrane protein . Lysosome membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, phagosome membrane ; Multi-pass membrane protein . Cell membrane ; Multi-pass membrane protein . |
| Expression | Ubiquitous. |
Additional Images
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Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12650-50
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