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Antibody Product Overview
| ELK.No | ES12732 |
| Product name | THIC rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB; ELISA;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 39 |
| Human Swiss-Prot | Q9BWD1 |
| Source | Rabbit |
| Isotype | IgG |
| Target | THIC |
| Fields | >>Fatty acid degradation;>>Valine, leucine and isoleucine degradation;>>Lysine degradation;>>Tryptophan metabolism;>>Pyruvate metabolism;>>Glyoxylate and dicarboxylate metabolism;>>Butanoate metabolism;>>Terpenoid backbone biosynthesis;>>Metabolic pathways;>>Carbon metabolism;>>Fatty acid metabolism;>>Fat digestion and absorption |
| Gene name | ACAT2 ACTL |
| Protein name | THIC |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 110460 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8CAY6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 308100 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q5XI22 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human THIC AA range: 320-370 |
| Specificity | This antibody detects endogenous levels of THIC at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 44kD |
| Observed band (KD) | |
| Background | The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014], |
| Function | catalytic activity:2 acetyl-CoA = CoA + acetoacetyl-CoA.,similarity:Belongs to the thiolase family.,subunit:Homotetramer., |
| Subcellular location | Cytoplasm, cytosol . |
| Expression |
Additional Images
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Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES12732-100
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