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Antibody Product Overview
| ELK.No | ES12780 |
| Product name | TCEA1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 6917 |
| Human Swiss-Prot | P23193 |
| Source | Rabbit |
| Isotype | IgG |
| Target | TCEA1 |
| Fields | |
| Gene name | TCEA1 GTF2S TFIIS |
| Protein name | TCEA1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 21399 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P10711 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 362479 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4KLL0 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human TCEA1 AA range: 50-100 |
| Specificity | This antibody detects endogenous levels of TCEA1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 33kD |
| Observed band (KD) | |
| Background | |
| Function | alternative products:Additional isoforms seem to exist,disease:A chromosomal rearrangement involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1.,function:Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.,miscellaneous:S-II binds to RNA-polymerase II in the absence of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TFS-II family.,similarity:Contains 1 TFIIS |
| Subcellular location | Nucleus. |
| Expression |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12780-50
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