STAR5 rabbit pAb

STAR5 rabbit pAb

AO-06-ES12932-50

STAR5 rabbit pAb 50μL

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€299.00
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Antibody Product Overview

ELK.NoES12932
Product nameSTAR5 rabbit pAb
ReactivityHuman; Mouse
ApplicationsWB;ELISA;IHC
Other name
Size50μL
Unit price ($)148
Human gene ID80765
Human Swiss-ProtQ9NSY2
SourceRabbit
IsotypeIgG
TargetSTAR5
Fields
Gene nameSTARD5
Protein nameSTAR5
Human gene linkView Human Gene
Human Swiss linkView Human Swiss-Prot
Mouse gene ID170460
Mouse gene linkView Mouse Gene
Mouse Swiss-ProtQ9EPQ7
Mouse Swiss linkView Mouse Swiss-Prot
Rat gene ID
Rat gene link
Rat Swiss-Prot
Rat Swiss link
ImmunogenSynthesized peptide derived from human STAR5 AA range: 129-179
SpecificityThis antibody detects endogenous levels of STAR5 at Human/Mouse
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
ClonalityPolyclonal
DilutionWB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
PurificationThe antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration1 mg/ml
Storage stability-20°C/1 year
Molecular Weight (Da)23kD
Observed band (KD)
BackgroundProteins containing a steroidogenic acute regulatory-related lipid transfer (START) domain are often involved in the trafficking of lipids and cholesterol between diverse intracellular membranes. This gene is a member of the StarD subfamily that encodes START-related lipid transfer proteins. The protein encoded by this gene is a cholesterol transporter and is also able to bind and transport other sterol-derived molecules related to the cholesterol/bile acid biosynthetic pathways such as 25-hydroxycholesterol. Its expression is upregulated during endoplasmic reticulum (ER) stress. The protein is thought to act as a cytosolic sterol transporter that moves cholesterol between intracellular membranes such as from the cytoplasm to the ER and from the ER to the Golgi apparatus. Alternative splicing of this gene produces multiple transcript variants. [provided by RefSeq, Jan 2016],
Functionfunction:May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.,similarity:Contains 1 START domain.,
Subcellular locationmitochondrion,cytosol,
Expression

Additional Images

Image 1
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
Image 2
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Immunohistochemical analysis of paraffin-embedded human oophoroma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES12932-50
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