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Antibody Product Overview
| ELK.No | ES12980 |
| Product name | SPS1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 22929 |
| Human Swiss-Prot | P49903 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SPS1 |
| Fields | >>Selenocompound metabolism;>>Metabolic pathways |
| Gene name | SEPHS1 SELD SPS SPS1 |
| Protein name | SPS1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 109079 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BH69 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human SPS1 AA range: 323-373 |
| Specificity | This antibody detects endogenous levels of SPS1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 43kD |
| Observed band (KD) | |
| Background | This gene encodes an enzyme that synthesizes selenophosphate from selenide and ATP. Selenophosphate is the selenium donor used to synthesize selenocysteine, which is co-translationally incorporated into selenoproteins at in-frame UGA codons. [provided by RefSeq, Sep 2010], |
| Function | catalytic activity:ATP + selenide + H(2)O = AMP + selenophosphate + phosphate.,caution:The conserved active site Cys (or selenocysteine) residue in position 29 is replaced by a Thr. However, as function in selenoprotein synthesis is proven, it is possible Cys-31 is the active site.,function:Synthesizes selenophosphate from selenide and ATP.,similarity:Belongs to the selenophosphate synthetase 1 family. Class II subfamily., |
| Subcellular location | [Isoform 1]: Cell membrane ; Peripheral membrane protein . Nucleus membrane ; Peripheral membrane protein .; [Isoform 2]: Cytoplasm .; [Isoform 3]: Cytoplasm .; [Isoform 4]: Cytoplasm . |
| Expression | [Isoform 1]: Gradually expressed during the cell cycle until G2/M phase and then decreases. ; [Isoform 2]: Gradually expressed during the cell cycle until G2/M phase and then decreases. ; [Isoform 3]: Gradually expressed during the cell cycle until S phase and then decreases. |
Additional Images
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Western blot analysis of lysates from AD293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12980-100
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