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Antibody Product Overview
| ELK.No | ES12982 |
| Product name | SPRE3 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 399473 |
| Human Swiss-Prot | Q2MJR0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SPRE3 |
| Fields | |
| Gene name | SPRED3 EVE-3 |
| Protein name | SPRE3 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 101809 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q6P6N5 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human SPRE3 AA range: 311-361 |
| Specificity | This antibody detects endogenous levels of SPRE3 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 45kD |
| Observed band (KD) | |
| Background | This gene encodes a protein with a C-terminal Sprouty-like cysteine-rich domain (SRY) and an N-terminal Ena/Vasodilator-stimulated phosphoprotein (VASP) homology-1 (EVH-1) domain. The encoded protein is a member of a family of proteins that negatively regulates mitogen-activated protein (MAP) kinase signaling, particularly during organogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012], |
| Function | function:Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase.,PTM:Phosphorylated on tyrosine.,similarity:Contains 1 SPR (sprouty) domain.,similarity:Contains 1 WH1 domain.,subunit:Interacts with Ras., |
| Subcellular location | Cell membrane ; Peripheral membrane protein . |
| Expression |
Additional Images
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Western blot analysis of lysates from K562 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES12982-100
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