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Antibody Product Overview
| ELK.No | ES13145 |
| Product name | SETBP rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 26040 |
| Human Swiss-Prot | Q9Y6X0 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SETBP |
| Fields | |
| Gene name | SETBP1 KIAA0437 |
| Protein name | SETBP |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 240427 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z180 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human SETBP AA range: 990-1040 |
| Specificity | This antibody detects endogenous levels of SETBP at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 176kD |
| Observed band (KD) | |
| Background | This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011], |
| Function | similarity:Contains 3 A.T hook DNA-binding domains.,subunit:Interacts with SET.,tissue specificity:Expressed in numerous tissues., |
| Subcellular location | Nucleus . |
| Expression | Expressed in numerous tissues. Expressed at low levels in myeloid and monocytic cells as well as in CD34+ cells; expression levels are higher in myeloid malignancies. |
Additional Images
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Western blot analysis of lysates from 293T cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13145-50
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