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Antibody Product Overview
| ELK.No | ES13187 |
| Product name | SCLY rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 51540 |
| Human Swiss-Prot | Q96I15 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SCLY |
| Fields | >>Selenocompound metabolism;>>Metabolic pathways |
| Gene name | SCLY SCL |
| Protein name | SCLY |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 50880 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JLI6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 363285 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q68FT9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human SCLY AA range: 367-417 |
| Specificity | This antibody detects endogenous levels of SCLY at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 49kD |
| Observed band (KD) | |
| Background | Selenocysteine lyase (SCLY; EC 4.4.1.16) catalyzes the pyridoxal 5-prime phosphate-dependent conversion of L-selenocysteine to L-alanine and elemental selenium (Mihara et al., 2000 [PubMed 10692412]).[supplied by OMIM, Mar 2008], |
| Function | catalytic activity:L-selenocysteine + reduced acceptor = selenide + L-alanine + acceptor.,cofactor:Pyridoxal phosphate.,function:Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium.,induction:Up-regulated in acute glomerulonephritis. Regulated by AP-1.,similarity:Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.,subunit:Homodimer., |
| Subcellular location | Cytoplasm, cytosol . |
| Expression |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13187-50
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