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Antibody Product Overview
| ELK.No | ES13188 |
| Product name | SC6A9 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB;ELISA;IHC |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 6536 |
| Human Swiss-Prot | P48067 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SC6A9 |
| Fields | >>Synaptic vesicle cycle |
| Gene name | SLC6A9 |
| Protein name | SC6A9 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 14664 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P28571 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 116509 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | P28572 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human SC6A9 AA range: 101-151 |
| Specificity | This antibody detects endogenous levels of SC6A9 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 78kD |
| Observed band (KD) | |
| Background | The amino acid glycine acts as an inhibitory neurotransmitter in the central nervous system. The protein encoded by this gene is one of two transporters that stop glycine signaling by removing it from the synaptic cleft. [provided by RefSeq, Jun 2016], |
| Function | function:Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May play a role in regulation of glycine levels in NMDA receptor-mediated neurotransmission.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:All GLYT-1 subtypes can be found in brain, kidney, pancreas, lung, placenta, liver. But GLYT-1C subtype is only found in the brain., |
| Subcellular location | Membrane; Multi-pass membrane protein. |
| Expression | Isoform GlyT-1A and isoform GlyT-1B can be found in brain, kidney, pancreas, lung, placenta and liver but isoform GlyT-1C is only found in brain. |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human cervical carcinoma. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13188-100
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