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Antibody Product Overview
| ELK.No | ES13194 |
| Product name | SATB1 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 6304 |
| Human Swiss-Prot | Q01826 |
| Source | Rabbit |
| Isotype | IgG |
| Target | SATB1 |
| Fields | |
| Gene name | SATB1 |
| Protein name | SATB1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 20230 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q60611 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human SATB1 AA range: 343-393 |
| Specificity | This antibody detects endogenous levels of SATB1 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.302% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq, Apr 2016], |
| Function | function:Binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA.,PTM:Sumoylated.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 CUT DNA-binding domains.,tissue specificity:Expressed predominantly in thymus., |
| Subcellular location | Nucleus matrix . Nucleus, PML body . Organized into a cage-like network anchoring loops of heterochromatin and tethering specialized DNA sequences (PubMed:12692553). When sumoylated, localized in promyelocytic leukemia nuclear bodies (PML NBs) (PubMed:18408014). . |
| Expression | Expressed predominantly in thymus. |
Additional Images
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Western blot analysis of lysates from Jarkat cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13194-100
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