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Antibody Product Overview
| ELK.No | ES13449 |
| Product name | RBM19 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | Probable RNA-binding protein 19 (RNA-binding motif protein 19) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 9904 |
| Human Swiss-Prot | Q9Y4C8 |
| Source | Rabbit |
| Isotype | IgG |
| Target | RBM19 |
| Fields | |
| Gene name | RBM19 KIAA0682 |
| Protein name | RBM19 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 74111 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8R3C6 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human RBM19 AA range: 276-326 |
| Specificity | This antibody detects endogenous levels of RBM19 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.254% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009], |
| Function | similarity:Belongs to the RRM MRD1 family.,similarity:Contains 6 RRM (RNA recognition motif) domains., |
| Subcellular location | Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm . Chromosome . In discrete foci distributed throughout the cytoplasm and nucleoplasm during the 4 to 8 cell stages and the morula stage, but not in the periphery of the nucleolar precursor body (NPB). During blastocyst development, becomes increasingly localized to the nucleolus and less to the cytoplasm. At the late blastocyst stage, localized predominantly in the nucleolus. Localized in the nucleolus during interphase and to the perichromosomal sheath during mitosis. Does not colocalize in the cytoplasm with GW182 in P-bodies. May translocate to the nucleolus upon early embryonic development (By similarity). Colocalizes with NPM1 during interphase. By late prophase, metaphase, anaphase and telophase, associates with the chromosome per |
| Expression | Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level). |
Additional Images
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Western blot analysis of lysates from AD293 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13449-100
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