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Antibody Product Overview
| ELK.No | ES13848 |
| Product name | PXK rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 54899 |
| Human Swiss-Prot | Q7Z7A4 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PXK |
| Fields | |
| Gene name | PXK |
| Protein name | PXK |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 218699 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BX57 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 306203 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q4FZZ1 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PXK AA range: 238-288 |
| Specificity | This antibody detects endogenous levels of PXK at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 64kD |
| Observed band (KD) | |
| Background | This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014], |
| Function | domain:The protein kinase domain is predicted to be catalytically inactive.,function:Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.,sequence caution:Translated as Gly.,similarity:Belongs to the protein kinase superfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 WH2 domain.,subcellular location:Also associates with the plasma membrane. Isoform 3 is present throughout the cell.,tissue specificity:Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis, expression of isoform 7 has yet to be demonstrated., |
| Subcellular location | Cytoplasm . Cell membrane ; Peripheral membrane protein . Also associates with the plasma membrane. Isoform 3 is present throughout the cell. |
| Expression | Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated. |
Additional Images
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Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13848-50
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