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Antibody Product Overview
| ELK.No | ES13881 |
| Product name | PSMD5 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 5711 |
| Human Swiss-Prot | Q16401 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PSMD5 |
| Fields | |
| Gene name | PSMD5 KIAA0072 |
| Protein name | PSMD5 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 66998 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q8BJY1 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PSMD5 AA range: 424-474 |
| Specificity | This antibody detects endogenous levels of PSMD5 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 55kD |
| Observed band (KD) | |
| Background | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a non-ATPase subunit of the 19S regulator base that functions as a chaperone protein during 26S proteasome assembly. [provided by RefSeq, Jul 2012], |
| Function | domain:Rich in dileucine repeats, which have been implicated in trafficking of a variety of transmembrane proteins.,function:Belongs to the 26S multisubunit protease, which is required for ubiquitin-dependent proteolysis. Does not bind ubiquitin polymers.,similarity:Belongs to the proteasome subunit S5B family.,subunit:26S protease is composed of a multicatalytic protease (proteasome) and a regulatory ATPase complex. Both are multisubunit structures that associate in the presence of ATP to form the protease. Subunit S5B is part of the regulatory complex., |
| Subcellular location | proteasome complex,nucleoplasm,cytosol,proteasome regulatory particle, base subcomplex,proteasome accessory complex, |
| Expression |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES13881-100
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