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Antibody Product Overview
| ELK.No | ES13991 |
| Product name | PPR17 rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB;IHC |
| Other name | |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 10842 |
| Human Swiss-Prot | O96001 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PPR17 |
| Fields | >>Long-term depression |
| Gene name | PPP1R17 C7orf16 GSBS |
| Protein name | PPR17 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 19051 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9Z2E4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PPR17 AA range: 75-125 |
| Specificity | This antibody detects endogenous levels of PPR17 at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000;IHC-p 1:50-300 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 17kD |
| Observed band (KD) | |
| Background | The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010], |
| Function | function:Inhibits protein phosphatase-2A and protein phosphatase-1.,PTM:Substrate for cGMP-dependent protein kinase.,tissue specificity:Highly expressed in cerebellum., |
| Subcellular location | intracellular, |
| Expression | Highly expressed in cerebellum. |
Additional Images
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Western blot analysis of lysates from U2OS cells, primary antibody was diluted at 1:1000, 4°over night
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Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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: AO-06-ES13991-50
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