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Antibody Product Overview
| ELK.No | ES14143 |
| Product name | PGTA rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Geranylgeranyl transferase type-2 subunit alpha (EC 2.5.1.60) (Geranylgeranyl transferase type II subunit alpha) (Rab geranyl-geranyltransferase subunit alpha) (Rab GG transferase alpha) (Rab GGTase alpha) (Rab geranylgeranyltransferase subunit alpha) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5875 |
| Human Swiss-Prot | Q92696 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PGTA |
| Fields | |
| Gene name | RABGGTA |
| Protein name | PGTA |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 56187 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9JHK4 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 58983 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q08602 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PGTA AA range: 312-362 |
| Specificity | This antibody detects endogenous levels of PGTA at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.146% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | |
| Function | catalytic activity:Geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate.,cofactor:Binds 1 zinc ion per dimer.,enzyme regulation:The enzymatic reaction requires the aid of a Rab escort protein (also called component A).,function:Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.,similarity:Belongs to the protein prenyltransferase subunit alpha family.,similarity:Contains 6 PFTA repeats.,subunit:Heterodimer of an alpha and a beta subunit, collectively called component B., |
| Subcellular location | plasma membrane,Rab-protein geranylgeranyltransferase complex, |
| Expression | Fetal brain,Lung,Thymus,Tongue, |
Additional Images
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Western blot analysis of lysates from SW480 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14143-50
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