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Antibody Product Overview
| ELK.No | ES14150 |
| Product name | PGM1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 5236 |
| Human Swiss-Prot | P36871 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PGM1 |
| Fields | >>Glycolysis / Gluconeogenesis;>>Pentose phosphate pathway;>>Galactose metabolism;>>Purine metabolism;>>Starch and sucrose metabolism;>>Amino sugar and nucleotide sugar metabolism;>>Metabolic pathways;>>Biosynthesis of nucleotide sugars |
| Gene name | PGM1 |
| Protein name | PGM1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 72157 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9D0F9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | P38652 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human PGM1 AA range: 318-368 |
| Specificity | This antibody detects endogenous levels of PGM1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.98% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 60kD |
| Background | The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Mar 2010], |
| Function | catalytic activity:Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:This enzyme participates in both the breakdown and synthesis of glucose.,polymorphism:Many polymorphic variants of PGM1 exist. 8 different alleles are known: PGM1*1+, PGM1*1-, PGM1*2+, PGM1*2-, PGM1*3+, PGM1*3-, PGM1*7+ and PGM1*7-. The sequence of PGM1*1+ is shown here.,similarity:Belongs to the phosphohexose mutase family.,subunit:Monomer., |
| Subcellular location | [Isoform 1]: Cytoplasm. |
| Expression | Cervix,Epithelium,Hypothalamus,Placenta,Skeletal muscle,Skin, |
Additional Images
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Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14150-100
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