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Antibody Product Overview
| ELK.No | ES14253 |
| Product name | PASD1 rabbit pAb |
| Reactivity | Human;Rat;Mouse; |
| Applications | WB |
| Other name | PAS domain-containing protein 1 (Cancer/testis antigen 63) (CT63) (OX-TES-1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 139135 |
| Human Swiss-Prot | Q8IV76 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PASD1 |
| Fields | |
| Gene name | PASD1 |
| Protein name | PASD1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | |
| Mouse gene link | |
| Mouse Swiss-Prot | |
| Mouse Swiss link | |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PASD1 AA range: 710-760 |
| Specificity | This antibody detects endogenous levels of PASD1 at Human |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.352% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 85kD |
| Background | This gene encodes a protein that is thought to function as a transcription factor. The protein is a cancer-associated antigen that can stimulate autologous T-cell responses, and it is therefore considered to be a potential immunotherapeutic target for the treatment of various hematopoietic malignancies, including diffuse large B-cell lymphoma. [provided by RefSeq, May 2010], |
| Function | function:May function as a transcription factor.,similarity:Contains 1 PAS (PER-ARNT-SIM) domain.,tissue specificity:Testis-specific. Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widespread expression seen in solid tumors and diffuse large B-cell lymphoma (DLBCL)-derived cell lines. Isoform 2 is expressed in all DLBCL-derived cell lines, while isoform 1 is preferentially expressed in cell lines derived from non-germinal center DLBCL., |
| Subcellular location | [Isoform 1]: Nucleus . Associates preferentially at the periphery of the nucleus with heterochromatin (PubMed:25936801). .; [Isoform 2]: Nucleus . Associates preferentially at the periphery of the nucleus with heterochromatin (PubMed:25936801). . |
| Expression | Testis-specific (PubMed:25936801). Expressed in a broad range of cancer cells, including melanoma, lung cancer, and breast cancer (at protein level). Testis-specific (PubMed:15162151). Found in histologically normal tissues from patients with uterus, lung and small intestine cancers. Widespread expression seen in solid tumors and diffuse large B-cell lymphoma (DLBCL)-derived cell lines. Isoform 2 is expressed in all DLBCL-derived cell lines, while isoform 1 is preferentially expressed in cell lines derived from non-germinal center DLBCL (PubMed:15162151). |
Additional Images
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Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14253-50
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