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Antibody Product Overview
| ELK.No | ES14282 |
| Product name | PA2GE rabbit pAb |
| Reactivity | Human; Mouse |
| Applications | WB |
| Other name | |
| Size | 100μL |
| Unit price ($) | 248 |
| Human gene ID | 30814 |
| Human Swiss-Prot | Q9NZK7 |
| Source | Rabbit |
| Isotype | IgG |
| Target | PA2GE |
| Fields | >>Glycerophospholipid metabolism;>>Ether lipid metabolism;>>Arachidonic acid metabolism;>>Linoleic acid metabolism;>>alpha-Linolenic acid metabolism;>>Metabolic pathways;>>Ras signaling pathway;>>Vascular smooth muscle contraction;>>Pancreatic secretion;>>Fat digestion and absorption |
| Gene name | PLA2G2E |
| Protein name | PA2GE |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 26970 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q9QUL3 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | |
| Rat gene link | |
| Rat Swiss-Prot | |
| Rat Swiss link | |
| Immunogen | Synthesized peptide derived from human PA2GE AA range: 58-108 |
| Specificity | This antibody detects endogenous levels of PA2GE at Human/Mouse |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1：500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | 16kD |
| Observed band (KD) | |
| Background | |
| Function | catalytic activity:Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.,cofactor:Binds 1 calcium ion per subunit.,function:PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a preference for arachidonic-containing phospholipids.,similarity:Belongs to the phospholipase A2 family.,tissue specificity:Restricted to the brain, heart, lung, and placenta., |
| Subcellular location | Secreted . Cytoplasm . Through binding to heparan sulfate proteoglycan, may be localized to cytoplasmic compartments enriched in anionic phospholipids. . |
| Expression | Restricted to the brain, heart, lung, and placenta. |
Additional Images
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Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14282-100
: 10 Items
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