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Antibody Product Overview
| ELK.No | ES14354 |
| Product name | OTX1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Homeobox protein OTX1 (Orthodenticle homolog 1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 5013 |
| Human Swiss-Prot | P32242 |
| Source | Rabbit |
| Isotype | IgG |
| Target | OTX1 |
| Fields | >>Signaling pathways regulating pluripotency of stem cells |
| Gene name | OTX1 |
| Protein name | OTX1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 18423 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | P80205 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 25646 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q63410 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human OTX1 AA range: 236-286 |
| Specificity | This antibody detects endogenous levels of OTX1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.61% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 38kD |
| Background | This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015], |
| Function | developmental stage:Embryo.,function:Probably plays a role in the development of the brain and the sense organs. Can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.,similarity:Belongs to the paired homeobox family. Bicoid subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Expressed in brain., |
| Subcellular location | Nucleus . |
| Expression | Expressed in brain. Detected in the anterior part of the neural fetal retina (at protein level). |
Additional Images
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Western blot analysis of lysates from HCT116 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14354-50
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