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Antibody Product Overview
| ELK.No | ES14366 |
| Product name | OSBL1 rabbit pAb |
| Reactivity | Human; Mouse;Rat |
| Applications | WB |
| Other name | Oxysterol-binding protein-related protein 1 (ORP-1) (OSBP-related protein 1) |
| Size | 50μL |
| Unit price ($) | 148 |
| Human gene ID | 114876 |
| Human Swiss-Prot | Q9BXW6 |
| Source | Rabbit |
| Isotype | IgG |
| Target | OSBL1 |
| Fields | |
| Gene name | OSBPL1A ORP1 OSBP8 OSBPL1 OSBPL1B |
| Protein name | OSBL1 |
| Human gene link | View Human Gene |
| Human Swiss link | View Human Swiss-Prot |
| Mouse gene ID | 64291 |
| Mouse gene link | View Mouse Gene |
| Mouse Swiss-Prot | Q91XL9 |
| Mouse Swiss link | View Mouse Swiss-Prot |
| Rat gene ID | 259221 |
| Rat gene link | View Rat Gene |
| Rat Swiss-Prot | Q8K4M9 |
| Rat Swiss link | View Rat Swiss-Prot |
| Immunogen | Synthesized peptide derived from human OSBL1 AA range: 229-279 |
| Specificity | This antibody detects endogenous levels of OSBL1 at Human/Mouse/Rat |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.209% sodium azide. |
| Clonality | Polyclonal |
| Dilution | WB 1:500-2000 |
| Purification | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration | 1 mg/ml |
| Storage stability | -20°C/1 year |
| Molecular Weight (Da) | |
| Observed band (KD) | 105kD |
| Background | This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms. [provided by RefSeq, Jul 2008], |
| Function | function:Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate.,similarity:Belongs to the OSBP family.,similarity:Contains 1 PH domain.,similarity:Contains 3 ANK repeats.,subunit:Interacts with VAPA., |
| Subcellular location | Late endosome . Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes. |
| Expression | Bone,Brain,Embryo,Epithelium,Kidney,Pancreas,Testicle, |
Additional Images
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Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
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: AO-06-ES14366-50
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